At an oral dose of 2000 mg/kg/working day in rats, maternal toxicity and deaths ended up witnessed with an increased incidence of early fetal resorption; spontaneous abortions happened in cynomolgus monkeys with the maternally toxic oral dose of 2000 mg/kg/day; there aren't any sufficient and well-controlled trials in pregnant women; https://gwendolynp888epd2.empirewiki.com/user