Q: Is there any contraindication applying Conolidine if using Jantovan, blood thinner. thanks.. A: There is restricted data on contraindications involving Conolidine and blood thinners like Jantovan. When the opiate receptor relies on G protein coupling for signal transduction, this receptor was observed to utilize arrestin activation for internalization https://arthurchhbu.blogdigy.com/a-review-of-conolidine-48370992