Also, at distinct concentrations, triptolide was discovered to induce the phosphorylation of p53 on the serine-fifteen residue in HepG2 cells. Activating the tumor suppressor gene p53 can induce the apoptosis of liver cancer cells 36. The pentacyclic triterpenoid celastrol has become identified as A serious bioactive metabolite of T. wilfordii https://pharmacologicalactionsoft56801.blogsmine.com/31909462/facts-about-triptolide-revealed