Contraindicated (one)pentobarbital will minimize the extent or effect of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with solid CYP3A4 inducers isn't recommended pentobarbital will decrease the extent or influence of alosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known. pentobar... https://alanu639bcd8.frewwebs.com/profile