Caloric restriction and intermittent fasting have also been proven to immediately inhibit the mTOR pathway, thus relieving the inhibition of the autophagy pathway to lead to apoptosis. Conversely, intermittent fasting has actually been revealed to activate AMPK, which inhibits mTOR from halting autophagy in fast developing cancer cells. Finally, https://directivepublications.org/world-journal-of-clinical-cancer-research/